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A cell-permeable phenylacetate compound that blocks Nur77 (TR3) LKB1 nuclear-sequestering function by antagonizing against Nur77-LKB1 interaction via direct binding at the LKB1 LBD/ligand binding domain ( K d
A cell-permeable cytoplasmic transduction peptide (CTP; YGRRARRRARR) fused to the NEMO binding domain peptide (NBD; TALDWSWLQTE) that acts as a potent inhibitor of TNFα-stimulated NF-κB activity (IC50∽ 50μM in HCT116 cells).
The Nrf2 Activator III, TAT-14 Peptide modulates the biological activity of Nrf2. This small molecule/inhibitor is primarily used for Biochemicals applications.
The Arp2/3 Complex Inhibitor I, Inactive Control, CK-689, also referenced under CAS 170930-46-8, controls the biological activity of Arp2/3. This small molecule/inhibitor is primarily used for Cell Structure applications.
GSA/VA Contract Available on GSA/VA contract for Federal Government customers. Learn More
Yield highly pure MBP-tagged recombinant proteins eluted in concentrated form and small volumes. Cytiva Life Sciences™ MBPTrap™ HP Prepacked Columns are prepacked with Dextrin Sepharose™ High Performance.
The MMP-2/MMP-9 Inhibitor III controls the biological activity of MMP-2/MMP-9. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.
A thiazolidinedione compound that acts as an anti-diabetic agent and serves as a potent and selective agonist of peroxisome proliferator-activated receptor-γ (PPARγ) (Kd ∽40 nM) in fat cells.
The CRAC Channel Inhibitor, BTP2, also referenced under CAS 223499-30-7, controls the biological activity of CRAC Channel. This small molecule/inhibitor is primarily used for Inflammation/Immunology applications.
The Calpain Inhibitor Set controls the biological activity of Calpain. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.
Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
Highly pure fluorescent exosome standards with superior performance, suitable for extracellular vesicle (EV) tracking studies, flow cytometry, and electron microscopy
A cell-permeable isoxazolocarboxamide compound that enhances the E-cadherin protein level in lung squamous cell carcinoma H520 and colorectal adenocarcinoma SW620 cells.